What Is the Synvisc-One Official Site?

Updated

Synviscone.com is the official U.S. brand website for Synvisc-One (hylan G-F 20), a single-injection treatment for osteoarthritis (OA) knee pain. It is a Sanofi US website aimed at U.S. residents, and it splits its content between patients and healthcare professionals. If you are looking for the manufacturer's own explanation of what the treatment is, who it is indicated for, and what to expect around an injection, this is the source to use — but it is a brand site, so it presents the product's case rather than a neutral comparison of options.

What the site covers

The site is organized around the patient journey, from understanding the condition to preparing for and recovering from treatment:

  • About knee osteoarthritis — background on OA of the knee and general treatment options
  • What is Synvisc-One — how the product works, pain relief and side effects, patient stories, and FAQs
  • Treatment with Synvisc-One — preparing for a doctor visit, what happens after an injection, and making the most of treatment
  • Knee exercise center — exercise videos, plus nutrition and weight loss and alternative therapies
  • Doctor Q&A — questions answered by a physician
  • Insurance coverage — a tool to check whether insurance covers Synvisc-One
  • Printable assessment — a form to bring to an appointment to simplify the discussion with your doctor

There is also a short overview video (the page notes it as "available shortly") and a separate section for U.S. healthcare professionals.

The indication, in the site's own terms

The site states that SYNVISC (hylan G-F 20) and SYNVISC-ONE (hylan G-F 20) are indicated for the treatment of pain in osteoarthritis of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen.

That indication matters for reading the rest of the site: the product is positioned as an option after simpler measures have not worked well enough, not as a first-line treatment.

Safety information the site leads with

Before trying Synvisc-One or SYNVISC, the site says to tell your doctor if you have had an allergic reaction — such as swelling of the face, tongue or throat, respiratory difficulty, rash, itching or hives — to SYNVISC, Synvisc-One, or any hyaluronan-based products. Full details are in the Important Safety Information and Prescribing Information linked from the site.

Who each part of the site is for

Audience What they get
U.S. patients and caregivers Condition background, product explanation, side effects, patient stories, FAQs, exercise and nutrition content, insurance coverage check, printable doctor-visit assessment
U.S. healthcare professionals A separate HCP section, reached through a confirmation prompt noting the site is intended for U.S. healthcare professionals only

The site also shows standard outbound-link notices when you leave the Sanofi US site, stating that Sanofi US does not review the content, accuracy, or completeness of external sites.

Practical notes before you use it

  • U.S. residents only. The site states this directly, and the HCP section repeats the restriction for professionals.
  • It is a brand site. Expect product-focused framing. For a balanced view of how injection therapy compares with other OA knee options, pair it with non-brand sources and your clinician.
  • No pricing is published on the page. The site offers an insurance coverage check rather than cost figures, so do not assume anything about what you would pay.
  • Use the printable assessment. It is designed to structure the conversation at your next appointment, which is the practical next step if you are considering the treatment.