What Is the pylorus.keet.net Website?

pylorus.keet.net hosts the full online edition of The Pyloric Sphincteric Cylinder in Health and Disease, a medical monograph by AD Keet. The book was originally published by Springer-Verlag in 1993, and the publisher later returned full copyright to the author so the complete work could be posted on the Internet for research use. If you need a detailed, book-length reference on the anatomy, physiology, and pathology of the human pylorus, this site is the primary source for that text.

What the site contains

The site presents the entire book, organized into 39 chapters plus front and back matter. The content is a single-author treatise rather than a collection of separate articles, so the chapters build on one another.

The central idea developed throughout is the sphincteric cylinder — a cylindrical muscular structure at the pylorus — as distinct from the older concept of a simple sphincteric ring. The book examines how this structure behaves in health and in disease.

Chapter coverage

The chapters fall into several broad groups:

• Foundational anatomy and physiology — the walls of the stomach and duodenum, the submucous coat, the mucous membrane, electrical potential difference at the gastroduodenal mucosal junction, arteries, veins, lymphatics, nerves, and regulatory peptides.
• Imaging and measurement methods — ultrasonography of normal anatomy, radiographic examination of normal motility, the pylorus at gastroscopy, manometry at the gastroduodenal junction, myoelectric activity, and radionuclides in the investigation of gastric emptying.
• Normal function and borderline states — the pylorus at rest (open or closed?), gastric tone, and pylorospasm.
• Congenital and structural conditions — congenital anomalies, partial or intramural gastric diverticulum, infantile hypertrophic pyloric stenosis, adult hypertrophic pyloric stenosis, and focal hypertrophy and focal spasm of the pyloric musculature in adults.
• Functional and reflux-related topics — nausea, retching and vomiting, duodenogastric reflux, and gastro-oesophageal reflux disease (GERD) and the pyloric sphincteric cylinder.
• Inflammatory and ulcerative disease — gastritis and erosions, gastric ulceration, and duodenal ulceration in relation to the sphincteric cylinder.
• Fistula and prolapse — pyloroduodenal fistula or acquired double pylorus, and prolapse of gastric mucosa into the duodenum.
• Malignancy — pyloric carcinoma, malignant lymphoma, malignancy at the gastro-oesophageal junction, and sessile polyps in the sphincteric cylinder.
• Systemic and other conditions — diabetes mellitus, and acid corrosive injuries.

How the research was done

The project originated in and was managed from the Department of Roentgenology at Tygerberg Hospital, the academic hospital of the Faculty of Medicine, University of Stellenbosch, South Africa.

A point worth noting for readers: the author states that roentgenology (barium meal or upper gastrointestinal series) was used here as an investigative rather than a diagnostic tool. In that specific research context, the author argues roentgenology has certain advantages over endoscopy — while acknowledging that endoscopy is currently the investigation of choice in upper gastrointestinal pathology. This framing matters if you are reading the book for clinical guidance rather than for the underlying anatomy and physiology.

The book also compares findings obtained across several modalities: gastroscopy, ultrasonography, manometry, radionuclide scintigraphy, myoelectric activity, and roentgenology.

Publication and access details

The stated aim of the online edition is to make the work easily accessible worldwide for research purposes.

Copyright and reuse

The site carries an explicit copyright notice. All rights are reserved, including translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or by any other means, and storage in data banks. Duplication of the publication or parts of it requires prior permission from the current publishers. The notice also states that no part may be stored in a retrieval system or transmitted in any form without prior permission.

In practical terms: you can read the full text on the site, but you should not reproduce or redistribute it without permission.

Contact

Feedback about the publication can be sent by email to [email protected].

Who this site is for

This resource suits readers who want the complete original text of a specialized monograph — for example, a researcher tracing how the sphincteric cylinder concept was developed, a student comparing the anatomy described by Cunningham (1906), Forssell (1913), and Torgersen (1942), or a clinician interested in how the author relates pyloric anatomy to conditions such as gastric and duodenal ulceration, certain types of gastritis, diabetes mellitus, and pyloric carcinoma.

It is a 1993 single-author work, so treat it as a historical and anatomical reference rather than a current clinical guideline. For present-day diagnostic decisions, the author's own note that endoscopy is the investigation of choice is the relevant caveat.