What Diseases and Pathological Conditions of the Pylorus Are Covered in The Pyloric Sphincteric Cylinder in Health and Disease?

Updated

The book covers a broad range of pyloric and gastroduodenal pathology, from congenital anomalies and motility disorders to ulceration, reflux, and malignancy. Its full chapter list is available on pylorus.keet.net, and the coverage is best understood as a systematic survey organized by condition type rather than a short clinical handbook. The list below reflects the chapters as published in the online edition.

Congenital and structural abnormalities

  • Congenital anomalies (Chapter 21)
  • Partial or intramural gastric diverticulum (Chapter 22)
  • Infantile hypertrophic pyloric stenosis (Chapter 23)
  • Adult hypertrophic pyloric stenosis (Chapter 24)
  • Focal hypertrophy and focal spasm of the pyloric musculature in adults (Chapter 25)

These chapters deal with conditions in which the anatomy or muscular structure of the pyloric region is abnormal, whether present from birth or acquired later.

Motility and functional disorders

  • Pylorospasm (Chapter 20)
  • Nausea, retching and vomiting (Chapter 26)
  • Duodenogastric reflux (Chapter 27)
  • Prolapse of gastric mucosa into the duodenum (Chapter 38)

The book develops the concept of a sphincteric cylinder rather than a simple sphincteric ring, and these chapters examine how disturbances of that structure relate to symptoms and to reflux of duodenal contents back into the stomach.

Inflammatory and ulcerative conditions

  • Gastritis and erosions in the pyloric sphincteric cylinder (Chapter 28)
  • Gastric ulceration and the pyloric sphincteric cylinder (Chapter 29)
  • Duodenal ulceration and the pyloric sphincteric cylinder (Chapter 30)
  • Acid corrosive injuries and the pyloric sphincteric cylinder (Chapter 39)

Ulceration and mucosal injury are treated in relation to the pyloric region specifically, rather than as general gastric or duodenal disease.

Reflux disease and related conditions

  • Gastro-oesophageal reflux disease (GERD) and the pyloric sphincteric cylinder (Chapter 32)

This chapter links the pyloric sphincteric cylinder to GERD, a connection that follows from the book's argument that pyloric function affects upstream events.

Fistula and acquired structural change

  • Pyloroduodenal fistula or acquired double pylorus (Chapter 31)

Malignancy

  • Pyloric carcinoma (Chapter 33)
  • Malignant lymphoma (Chapter 34)
  • Malignancy at the gastro-oesophageal junction (Chapter 35)
  • Sessile polyps in the sphincteric cylinder (Chapter 36)

Systemic and metabolic disease

  • Diabetes mellitus (Chapter 37)

Diabetes is included because of its recognized effects on gastric and pyloric motility.

How the conditions are investigated

The book compares findings from several investigative methods across these conditions, including gastroscopy, ultrasonography, manometry, radionuclide scintigraphy, myoelectric activity, and roentgenology (barium meal or upper gastrointestinal series). The author notes that roentgenology was used as an investigative rather than a diagnostic tool in this work, while acknowledging that endoscopy is currently the investigation of choice in upper gastrointestinal pathology.

What the coverage is and is not

The scope is defined by the book's central anatomical concept: conditions are discussed insofar as they relate to the pyloric sphincteric cylinder. It is a research-oriented treatise first published by Springer-Verlag in 1993 and later made available in full online, not a current clinical guideline. For decisions about diagnosis or treatment, the relevant current literature and clinical guidance should be consulted alongside it.