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  1. BLAST

    blast.ncbi.nlm.nih.gov

    The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches. BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families.

Practical guides

What Is Sequence Homology and How Do You Infer It from BLAST Results?
Sequence homology is a conclusion about shared ancestry, not a measurement. Two sequences are homologous if they descend from a common ancestral sequ…