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  1. BLAST

    blast.ncbi.nlm.nih.gov

    The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches. BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families.

Practical guides

What Is Sequence Similarity and How Does BLAST Measure It?
Sequence similarity is the degree to which two biological sequences — DNA, RNA, or protein — match in local regions when aligned side by side. BLAST …