mbresearch.com

MB Research Laboratories is a contract research organization (CRO) that specializes in toxicology testing and safety assessments for regulated products. According to the company, it has supported pharmaceuticals, medical devices, chemicals, and consumer products with regulatory-ready safety studies for over 50 years. Its work is aimed at companies that need GLP-compliant studies aligned with OECD, EPA, ISO, and DOT standards, particularly for cosmetics, pharmaceuticals, medical devices, chemicals, and consumer products.

What MB Research Does

MB Research provides toxicology and safety assessment services rather than manufacturing or selling products. Its stated focus is generating data that supports regulatory submissions and hazard classification. The company describes its studies as GLP-compliant and aligned with international standards, which matters when results must be accepted by regulators in multiple markets.

The core service areas listed on its site include:

• Eye and skin safety testing — OECD TG 437, 492, 439, and 431 methods for eye irritation, dermal irritation, and corrosion testing using validated in vitro methods.
• Biocompatibility testing — ISO 10993 medical device safety, covering cytotoxicity, irritation, and sensitization studies.
• Acute toxicity testing — an OECD "six-pack" (TG 420, 423, 425, 402, 403) supporting hazard classification and regulatory safety assessments.
• Skin sensitization testing — OECD TG 442 methods, using in vitro and in vivo approaches to evaluate allergic contact dermatitis potential.
• Regulatory toxicology testing — GLP-compliant safety studies supporting global regulatory submissions under OECD, EPA, ISO, and DOT standards.

Who It Serves

MB Research organizes its services around five core industries. The table below summarizes what the company says it offers each one.

Why the Standards Matter

The value of a CRO like MB Research depends on whether its studies will be accepted by the regulator reviewing your product. Two labels carry most of that weight:

• GLP (Good Laboratory Practice) — a quality system for how nonclinical safety studies are planned, performed, monitored, recorded, and reported. Regulators generally expect GLP compliance for studies used in submissions.
• OECD / ISO test guidelines — standardized methods (for example, OECD TG 492 for eye irritation or ISO 10993 for device biocompatibility) that make results comparable across labs and jurisdictions.

If your product needs to clear more than one market, matching the study to the relevant guideline is usually the deciding factor in choosing a lab.

When to Consider MB Research

MB Research is a reasonable fit if you need:

• GLP-compliant toxicology data for a regulatory submission or hazard classification.
• In vitro alternatives for eye, skin, or sensitization endpoints, especially for cosmetics where animal testing is restricted.
• Biocompatibility testing for a medical device under ISO 10993.
• Acute toxicity studies across multiple exposure routes.

It is likely not the right fit if you need clinical trials, manufacturing, or non-toxicology analytical work, since the site describes a toxicology and safety assessment focus.

Practical Next Step

The site offers a "Get a quote" path and "Learn More" pages for each assay type. To get a useful response, come prepared with your product type, the target market(s), the endpoint(s) you need tested, and any guideline the regulator has specified. Pricing is not published on the page, so cost and turnaround need to be confirmed directly with the lab.

MB Research Laboratories is a contract research organization (CRO) that provides GLP-compliant toxicology and safety testing for cosmetics, pharmaceuticals, medical devices, chemicals, and consumer products. To request a quote, use the "Get a quote" call to action on mbresearch.com and describe the assay or study you need. The site does not publish a quote form, pricing, or a stated response time, so the practical path is to contact the lab with your test type, regulatory framework, and product details and let them scope the study.

What to have ready before you contact them

A quote is only as specific as the information you provide. MB Research organizes its services by assay type and by industry, so framing your request in those terms speeds up scoping.

Prepare the following:

• Test category — for example eye or skin safety, biocompatibility, acute toxicity, or skin sensitization.
• Applicable standard or guideline — the OECD test guideline (TG) or ISO standard your submission requires.
• Regulatory context — the agency or framework you are submitting to (OECD, EPA, ISO, DOT, or a specific market such as the EU).
• Product or material type — raw material, formula, finished product, or medical device.
• Study design questions — in vitro vs. in vivo, number of articles or formulations, and any endpoints you already know you need.

Map your need to a service line

MB Research lists its assays in two ways: by type and by industry. Matching your request to one of these categories makes the first contact more productive.

Popular assays by type

Industries served

MB Research states it has served five core industries for over 50 years:

• Cosmetics — safety assessments for raw materials, formulas, and finished products, including in vitro alternatives for ocular irritation, dermal irritation, phototoxicity, and corrosivity, with attention to frameworks such as the EU Cosmetics Directive (76/768/EEC).
• Consumer products — acute toxicology and safety assessment including oral, dermal, and inhalation exposure studies, aimed at CPSC, EPA, and international requirements.
• Pharmaceuticals, medical devices, and chemicals — regulatory-ready safety studies under GLP.

If your product falls into one of these categories, say so explicitly; it tells the lab which regulatory expectations apply.

How to submit the request

1. Go to mbresearch.com and use the "Get a quote" call to action.
2. State the assay or study type using the names above (for example, "OECD TG 492 eye irritation" or "ISO 10993 biocompatibility").
3. Name the regulatory submission or market the data must support.
4. Describe the test article: material, formulation, or device, and how many need testing.
5. Ask any scoping questions you have — for example whether an in vitro method can replace an in vivo endpoint for your case.

The expected result is a scoped study proposal and quote from the lab. Because the site does not publish a form structure, pricing, or turnaround, treat the first reply as the point where those details get defined.

Common sticking points

• No published pricing. The site shows no price list or payment details, so do not assume a rate or a free consultation. Ask for the quote directly.
• Guideline selection matters. Choosing the wrong OECD TG or ISO part can mean the study does not support your submission. If you are unsure, describe the regulatory goal and let the lab recommend the method.
• In vitro vs. in vivo. MB Research emphasizes 21st-century approaches and in vitro alternatives for cosmetics; if avoiding animal testing is a requirement, state that up front.
• Multiple assays. Acute toxicity is often requested as a "six-pack." If you need a battery rather than a single test, say so to avoid a piecemeal quote.

What you can and cannot confirm from the website

You can confirm the service categories, the standards referenced, the industries served, and the existence of a "Get a quote" entry point. You cannot confirm pricing, response times, required form fields, or whether a consultation is free — none of that is published. For those, the quote request itself is the way to get an answer.

MB Research Laboratories is a contract research organization (CRO) that provides GLP-compliant toxicology and safety assessment services, with more than 50 years of experience. Its testing menu is organized around four main areas: eye and skin safety, biocompatibility, acute toxicity, and skin sensitization — all aligned to OECD, ISO, EPA, and DOT standards. This makes it relevant if you need regulatory-ready safety data for cosmetics, pharmaceuticals, medical devices, chemicals, or consumer products.

Eye and Skin Safety Testing

This category covers eye irritation, dermal irritation, and corrosion testing using validated in vitro methods. The assays cited on the site follow these OECD test guidelines:

• OECD TG 437 — Bovine Corneal Opacity and Permeability (BCOP) test for eye irritation
• OECD TG 492 — Reconstructed human cornea-like epithelium (RhCE) test for eye irritation
• OECD TG 439 — In vitro skin irritation test
• OECD TG 431 — In vitro skin corrosion test

These methods are designed to reduce reliance on animal models while still meeting rigorous scientific standards. They are commonly used for raw materials, formulas, and finished cosmetic and personal care products.

Biocompatibility Testing (ISO 10993)

For medical devices, MB Research conducts biocompatibility studies supporting device safety evaluations under ISO 10993. The services include:

• Cytotoxicity testing
• Irritation testing
• Sensitization studies

These are the core endpoints typically required for device biocompatibility assessments before regulatory submission.

Acute Toxicity Testing (Six-Pack)

The acute toxicity six-pack supports hazard classification and regulatory safety assessments. The site lists these OECD test guidelines:

• OECD TG 420 — Acute oral toxicity, fixed dose procedure
• OECD TG 423 — Acute oral toxicity, acute toxic class method
• OECD TG 425 — Acute oral toxicity, up-and-down procedure
• OECD TG 402 — Acute dermal toxicity
• OECD TG 403 — Acute inhalation toxicity

This integrated approach covers oral, dermal, and inhalation exposure routes.

Skin Sensitization Testing (OECD TG 442)

MB Research offers both in vitro and in vivo approaches for evaluating allergic contact dermatitis potential under OECD TG 442 methods. This is relevant for ingredients and products where sensitization potential must be characterized for regulatory dossiers.

Regulatory Toxicology Across Standards

Beyond individual assays, MB Research provides GLP-compliant safety studies supporting global regulatory submissions. The standards referenced include:

Industries Served

MB Research works across five core industries:

• Cosmetics — GLP-compliant safety assessments for raw materials, formulas, and finished products, including in vitro alternatives for ocular irritation, dermal irritation, phototoxicity, and corrosivity. The lab also helps brands navigate frameworks such as the EU Cosmetics Directive (76/768/EEC).
• Consumer products — End-to-end acute toxicology including oral, dermal, and inhalation exposure studies, designed to meet CPSC, EPA, and international requirements. This covers cleaning products, household chemicals, and personal care items.
• Pharmaceuticals, medical devices, and chemicals — Regulatory-ready safety studies supporting submissions in these sectors.

How to Decide If This Fits Your Needs

Choose MB Research if you need:

• GLP-compliant studies for a regulatory submission (OECD, EPA, ISO, or DOT)
• In vitro alternatives for eye or skin irritation and corrosion
• ISO 10993 biocompatibility endpoints for a medical device
• Acute toxicity data across multiple exposure routes
• Skin sensitization testing under OECD TG 442

If your project requires only non-GLP exploratory work or assays outside these categories, you would need to confirm scope directly with the lab. The site provides a quote request option for specific project discussions.

GLP-compliant toxicology testing means the safety study was planned, performed, recorded, and archived under Good Laboratory Practice quality systems, so the resulting data can be submitted to regulators as part of a safety assessment. It matters most when a submission depends on study data being accepted by agencies such as the EPA or international bodies, and when the study must follow a recognized test guideline (OECD, ISO, EPA, or DOT). MB Research Laboratories is a contract research organization (CRO) that positions its toxicology services this way: GLP-compliant studies supporting global regulatory submissions for pharmaceuticals, medical devices, chemicals, and consumer products.

Why "GLP-compliant" is different from "a good study"

A scientifically sound study is not automatically a regulatory-ready one. GLP adds the controls that let a reviewer trust the data:

• Defined protocols and standard operating procedures so the study design is fixed before it starts.
• Documented roles and training for personnel running and overseeing the study.
• Raw data capture and traceability, so every reported value can be traced back to its source.
• Equipment calibration and facility controls that establish the conditions under which data were generated.
• Archiving that preserves records for the period regulators require.
• A quality assurance function independent of the study staff, auditing the work and reporting to management.

The practical consequence: when a regulator reviews a submission, GLP documentation is what allows the study to stand as evidence rather than as an internal finding.

How GLP compliance connects to test guidelines

GLP and test guidelines are two different things, and submissions usually need both.

A study can follow an OECD guideline without being GLP-compliant, and it can be run under GLP without following a recognized guideline. For a regulatory submission, the useful combination is a guideline-based design executed under GLP.

What this looks like across product types

MB Research organizes its work by assay type and by industry, which maps onto how regulatory requirements differ:

• Pharmaceuticals, chemicals, and consumer products — acute toxicity testing aligned with OECD TG 420, 423, 425, 402, and 403, supporting hazard classification and regulatory safety assessments.
• Medical devices — biocompatibility studies under ISO 10993, covering cytotoxicity, irritation, and sensitization to support device biocompatibility evaluations.
• Cosmetics and personal care — in vitro alternatives for ocular irritation, dermal irritation, phototoxicity, and corrosivity, aimed at reducing reliance on animal models while meeting scientific standards. MB Research notes work within frameworks such as the EU Cosmetics Directive (76/768/EEC).
• Consumer products broadly — oral, dermal, and inhalation exposure studies intended to meet CPSC, EPA, and international requirements.

The recurring pattern: the guideline and the regulatory framework change by product, but the GLP layer is what makes the data submittable.

Choosing a lab: what to verify

If you are selecting a CRO for a submission-bound study, these are the questions that determine whether the data will be usable:

1. Is the specific study you need offered under GLP? Ask for the compliance statement for that assay, not the lab's general claim.
2. Which guideline does the design follow? For eye and skin work, confirm the OECD TG number; for devices, confirm the relevant ISO 10993 part.
3. Which regulatory frameworks does the lab routinely support? MB Research cites OECD, EPA, ISO, and DOT standards, and names CPSC and EU Cosmetics Directive requirements among the frameworks it helps clients navigate.
4. Does the lab have a track record in your product class? MB Research states over 50 years of GLP-compliant toxicology and safety assessment work across five core industries.
5. Can it support the submission, not just the benchwork? Ask how study reports are structured for the agency you are filing with.

Common points of confusion

• "GLP-certified" is not a standard term. GLP compliance is typically established through inspection and adherence to the applicable national GLP regulations, not a single universal certificate.
• A validated in vitro method is not automatically GLP-compliant. Validation addresses whether the method measures what it claims; GLP addresses how the study was run and documented.
• Guideline numbers are not interchangeable. OECD TG 437, 492, 439, and 431 address different endpoints, so the correct one depends on the claim you need to support.
• One study rarely covers every market. Because agencies differ, confirm that the study design and report format match each jurisdiction you plan to file in.

Where to start

If your goal is a regulatory submission, work backward from the requirement: identify the agency and framework, identify the guideline the agency expects, then confirm the lab runs that guideline under GLP and has done so for your product type. MB Research's service pages are organized by assay type and industry, which makes it straightforward to check whether a specific test — eye and skin safety, biocompatibility, acute toxicity, or skin sensitization — is offered under the standards your submission requires.

MB Research Laboratories is a contract research organization (CRO) that provides GLP-compliant toxicology and safety assessment services across five core industries: cosmetics, pharmaceuticals, medical devices, chemicals, and consumer products. If your company needs regulatory-ready safety studies — particularly acute toxicity, in vitro eye/skin testing, or biocompatibility work — and operates in one of those five sectors, MB Research is structured to serve you. The sections below break down what each industry actually gets, so you can judge fit before requesting a quote.

The five core industries at a glance

Cosmetics: in vitro alternatives and EU compliance

MB Research positions itself as a long-standing toxicology partner for cosmetic and personal care brands, covering raw materials, formulas, and finished products. The distinguishing feature for this industry is its emphasis on 21st-century risk assessment approaches — specifically in vitro alternatives such as ocular irritation, dermal irritation, phototoxicity, and corrosivity testing — which reduce reliance on animal models.

The relevant validated methods appear in the site's assay listings: OECD TG 437 and 492 (eye irritation), 439 (skin irritation), and 431 (skin corrosion). For brands selling into the EU, MB Research also states it helps navigate the EU Cosmetics Directive (76/768/EEC).

Choose this fit if you are a cosmetics or personal care company that needs in vitro safety data for ingredient validation or new product development, especially with EU market requirements in view.

Medical devices: ISO 10993 biocompatibility

For device manufacturers, MB Research offers biocompatibility testing aligned with ISO 10993, including cytotoxicity, irritation, and sensitization studies that support device biocompatibility evaluations. This is a narrower, standard-driven scope than the cosmetics or consumer product offerings, so the decision here is straightforward: if your device submission requires ISO 10993 biocompatibility endpoints, this falls within their stated service set.

Pharmaceuticals, chemicals, and consumer products

These three industries share a reliance on acute and regulatory toxicology:

• Pharmaceuticals — GLP toxicology testing supporting regulatory safety assessments, positioned as "regulatory-ready" for submissions.
• Chemicals — the acute toxicity "six-pack" under OECD TG 420, 423, 425, 402, and 403, supporting hazard classification and regulatory safety assessments.
• Consumer products — end-to-end acute toxicology including oral, dermal, and inhalation exposure studies, aimed at CPSC, EPA, and international requirements. The site notes this is driven partly by growing public scrutiny of ingredient safety, and lists cleaning products and household chemicals among the evaluated categories.

How to decide whether MB Research fits

Work through these conditions in order:

1. Industry match — Are you in cosmetics, pharma, medical devices, chemicals, or consumer products? The site states these are its five core industries; other sectors are not described.
2. Test type match — Do you need acute toxicity, eye/skin safety, skin sensitization, biocompatibility, or general GLP regulatory toxicology? These are the assay categories listed.
3. Standard match — Do your submissions reference OECD, EPA, ISO, or DOT standards? MB Research states its studies are GLP-compliant and aligned to these frameworks.
4. Regulatory submission goal — If your purpose is a global regulatory submission requiring GLP-compliant data, that is the stated use case.

If all four line up, the next step is requesting a quote through the site. Note that pricing is not published on the page, so cost and turnaround must be confirmed directly — do not assume any pricing or access terms from the site's absence of them.

What the page does not tell you

The source material describes service categories and regulatory alignment but does not list specific assay prices, turnaround times, or capacity limits. For a buying decision, treat those as open items to raise in a quote request. The one concrete credibility signal available is tenure: MB Research states it has provided these services for over 50 years.