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What is the Microscopy and Imaging Center at Texas A&M University?
The Microscopy and Imaging Center (MIC) at Texas A&M University is a shared research facility that supports imaging work across basic and applied sciences, offering advanced electron and light microscopy instruments along with related training. Its homepage describes the mission as promoting cutting-edge research through research and development activities, and it lists instruments such as a Leica SP8 confocal system with STED and FLIM, an FEI Quanta 600 field-emission SEM, a TFS Helios 5 CX cryo dual-beam FIB-SEM, and a JEOL 1200 EX TEM, with more instruments available.
Who it serves and how it is used
- Texas A&M students and researchers new to a technique. The MIC runs a free Scanning Electron Microscopy workshop (November 3–4, 2026, in person and via Zoom) covering SEM principles, resolution and contrast, and basic sample preparation, with hands-on sessions capped at five registrants.
- Campus and external research groups needing specialized imaging. The center notes that data acquired at the MIC supports research across campus and beyond, and it links articles citing use of the facility, including cover art in Macromolecular Materials and Engineering featuring TEM work and confocal imaging used to study tick neuropeptides.
- Researchers choosing between light and electron microscopy. Confocal and STED suit fluorescent labeling and live or thick samples, while SEM, FIB-SEM and TEM suit surface structure, serial sectioning and ultrastructure.
A practical next step
If you are planning a project, start with the technique rather than the instrument: decide whether you need fluorescence localization, surface topography or internal ultrastructure, then check the MIC instrument list and workshop offerings to see which system and training path fit. For broader context on shared imaging facilities, see Microscopy and Imaging Center.
Which instruments are available at the Microscopy and Imaging Center, such as confocal, SEM, or TEM, and how do I choose the right one for my sample?
The Microscopy and Imaging Center at Texas A&M lists confocal, electron microscopy and related systems, so the practical choice is less about which instrument is "best" and more about what information you need from the sample. The page names a Leica SP8 confocal with STED and FLIM, an FEI Quanta 600 field-emission SEM, a TFS Helios 5 CX DualBeam cryo FIB-SEM, and a JEOL 1200 EX TEM, with further instruments listed behind a "More Instruments" link on Microscopy and Imaging Center.
Matching instrument to sample
| If your question is… | Start with | Why |
|---|---|---|
| Where is a labelled molecule inside an intact cell or tissue? | Confocal (Leica SP8) | Optical sectioning of fluorescently tagged samples; STED and FLIM extend this to super-resolution and lifetime measurements |
| What does the surface or near-surface structure look like at high resolution? | SEM (FEI Quanta 600) | Surface topography and contrast on bulk samples |
| I need 3D structure at electron resolution, or want to mill into a frozen sample | DualBeam cryo FIB-SEM (Helios 5 CX) | Combines imaging with focused-ion-beam sectioning |
| I need internal ultrastructure through a thin specimen | TEM (JEOL 1200 EX) | Transmission through thinned sections reveals organelles and material nanostructure |
A concrete reader scenario: a graduate student with fluorescently tagged tick tissue wants to confirm that a neuropeptide labels midgut muscle. Confocal is the natural first stop because the signal is optical and the sample can stay intact; the page notes published work using confocal to fluorescently tag tick kinin neuropeptide. If the same student later needs to see membrane detail around that muscle, the question shifts to electron microscopy and the sample preparation changes completely.
How to decide
Work backwards from the output you need: a fluorescence image of a whole structure, a surface image, a 3D volume, or a cross-sectional ultrastructure image. Then check sample constraints—thickness, whether it can be fixed, whether it must stay frozen, and whether it must be labelled. The site's free SEM workshop for Texas A&M participants covers basic SEM principles, resolution and contrast factors, and sample preparation, which is a sensible entry point if you are new to electron microscopy. For anything beyond the listed systems, use the "More Instruments" page and confirm suitability with center staff before preparing samples, since preparation choices are hard to reverse.
How do I schedule instrument time or get trained to use the Microscopy and Imaging Center's equipment?
Instrument time and training at the Microscopy and Imaging Center (MIC) are arranged through the center rather than by walking up to an instrument. Training is typically tied to a specific instrument and often starts with a workshop or a staff-led session, after which users schedule time on that equipment. The clearest published entry point is the MIC's free Scanning Electron Microscopy Workshop for Texas A&M participants new to SEM, which covers basic SEM principles, resolution and contrast, and sample preparation, with in-person and Zoom presentations and hands-on sessions capped at five registrants.
Practical path for a new user
- Identify the technique your project needs (for example confocal or STED/FLIM imaging, FE-SEM, dual-beam cryo FIB-SEM, or TEM) and check which MIC instrument fits.
- Contact MIC staff to ask about training requirements and scheduling for that instrument; confirm whether your group is internal or external, since access and charges usually differ.
- Complete the required training or workshop before booking instrument time.
- Book time according to the center's scheduling process and plan sample preparation, since preparation often determines whether a session succeeds.
For a concrete case: a graduate student who needs fluorescent imaging of tissue sections should ask about confocal training and the Leica SP8 system first, then reserve time only after a staff member confirms sample-prep requirements. A materials researcher needing cross-sections should ask about the Helios 5 CX DualBeam cryo FIB-SEM, which has different training and prep demands.
Related facilities with public training and scheduling information include Example; always verify details with the MIC directly, as procedures and eligibility can change.
For the next step, email the MIC with your technique, sample type, and whether you are Texas A&M-affiliated, and ask for the current training checklist and scheduling instructions for that instrument.
What sample preparation services or guidance does the center provide for electron and confocal microscopy?
The Microscopy and Imaging Center at Texas A&M provides sample-preparation guidance mainly through training and workshop instruction rather than as a standalone, listed service. The clearest evidence on the page is a free Scanning Electron Microscopy workshop for Texas A&M students and researchers new to SEM, whose presentations cover basic sample preparation techniques alongside SEM principles, resolution and contrast. Hands-on sessions are capped at five registrants each and run in person or via Zoom, which suggests the preparation content is introductory and demonstration-based. The page does not itemize confocal-specific preparation services, nor does it describe routine preparation as a fee-based offering, so anyone needing sectioning, staining or critical-point drying should confirm availability directly with center staff before planning an experiment.
What the page supports
- SEM preparation teaching: basic sample preparation is an explicit workshop topic, aimed at newcomers.
- Instrument context: the center lists confocal (Leica SP8 with STED and FLIM), SEM (FEI Quanta 600), dual-beam cryo FIB-SEM (TFS Helios 5 CX) and TEM (JEOL 1200 EX) systems, so guidance can plausibly be matched to the instrument you intend to use.
- Research use: the page notes that data acquired at the center supports research across campus and beyond, indicating a working service lab rather than a teaching-only facility.
Practical next step
Before booking time, ask two questions: whether preparation is done by users or by staff, and whether your sample type (hydrated, beam-sensitive, fluorescently labelled) needs cryo or conventional processing. A reader preparing fluorescently labelled tissue for confocal work, for example, should confirm which fixation and mounting protocols the center recommends, since the page's preparation detail is framed around SEM. For broader method background while you wait, Microscopy and Imaging Center is the authoritative starting point for the center's own events and instrument list.
Is the free Scanning Electron Microscopy workshop suitable for beginners, and how do I register?
Yes. The workshop is explicitly intended for students and researchers who are new to scanning electron microscopy, so no prior SEM experience is implied. The presentations cover basic imaging principles, the factors that affect resolution and contrast, and basic sample preparation — a sensible starting sequence for someone who will either send samples to a facility or begin operating an instrument.
What the format means for a beginner
- Talks plus hands-on. The lecture portion is offered both in person (ILSB 1143) and online via Zoom, so you can attend remotely if travel is difficult. The hands-on sessions are capped at five registrants each, which keeps instrument time personal but also means those seats are the binding constraint.
- Free for Texas A&M participants. The page states the workshop is free of charge for Texas A&M University participants; if you are outside the university, confirm eligibility and any fee before planning around it.
- Dates listed: November 3–4, 2026, with sessions running 10:00 am–4:00 pm and 1:00 pm–4:00 pm. Treat these as the posted schedule and re-check closer to the date.
How to register
Registration is handled through a "Register Here" link on the workshop announcement on the center's site, Microscopy and Imaging Center. Open the workshop post, follow that link, and register early if you want a hands-on slot rather than only the presentations.
A practical next step
Before registering, decide which outcome you need: general literacy for interpreting SEM images in papers, or the ability to prepare and image your own samples. If it is the latter, email the center after registering to ask whether your sample type (biological, hydrated, beam-sensitive, or requiring coating) will be covered in the hands-on session — that determines whether the workshop alone is enough or whether you should also book a follow-up consultation.
How do I acknowledge or cite the Microscopy and Imaging Center in publications that use data acquired there?
The Microscopy and Imaging Center at Texas A&M University does not publish a citation format on its homepage. The page confirms that data acquired at the MIC is used in research across campus and beyond, but it gives no prescribed acknowledgment wording. Contact the center directly before you submit, and ask for its current acknowledgment and citation policy.
What to ask the center
- The exact acknowledgment text it prefers for publications that use MIC data.
- Whether it wants instrument names and facility staff credited, and in what form.
- Whether it issues a facility DOI or RRID that you should cite.
- Whether the policy differs for hands-on users versus assisted sessions.
A practical default
If no policy is supplied, use a short methods sentence naming the facility and the specific instrument, then a separate acknowledgment line. For example: "Imaging was performed at the Microscopy and Imaging Center, Texas A&M University, using the [instrument name]." Keep the instrument name consistent with what the center lists, such as the Leica SP8 confocal or the FEI Quanta 600 FE-SEM. Confirm the official wording with the center rather than relying on a template.
Why it matters
A clear acknowledgment makes the facility's contribution traceable and helps the center demonstrate use in grant reporting and publications. If you are new to the instruments, the center's free Scanning Electron Microscopy Workshop for Texas A&M participants covers basic SEM principles, resolution and contrast, and sample preparation, which can help you describe methods accurately.
Next step
Email the center with your manuscript's methods section and ask it to confirm or correct the acknowledgment before submission. For context on the facility's scope, see Microscopy and Imaging Center.
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